1 week ago - Common ailments in domestic guinea pigs include respiratory tract infections, diarrhea, scurvy (vitamin C deficiency, typically characterized by sluggishness), abscesses due to infection (often in the neck, due to hay embedded in the throat, or from external scratches), and infections by lice, mites, or fungus.
Cell adhesion collection includes cell surface receptors and their extracellular matrix ligands
OBJECTIVE: To evaluate the expression of vascular cell adhesion molecules (VCAM-1) and eotaxin and their transcription factors NF-kappa B and AP-1 in bronchi and bronchioles (with surrounded lung tissue), and to investigate the mechanisms for eosinophil chemotaxis to the lungs in a guinea pig model of asthma.
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In this study, we have used a monoclonal antibody to investigate the role of the WH-30 protein on the sperm surface in the formation of the junctional zones between adjacent guinea pig sperm in rouleaux.
In summary, human and guinea-pig leukocytes express binding activity to both FN and hVCAM-1. A specific VLA-4 blocking monoclonal antibody, TY 21.6, inhibited U937 and BAL cell binding to hVCAM-1, but only inhibited FN binding with U937 cells.
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70-71) a. Punctured with a mechanically-activated lancet: blood collected in capillary tubes b. Allows frequent, multiple small volume samples to be collected K. Anesthesia of Guinea Pigs 1. General considerations a. Fasting for 12 hours prior to anesthesia recommended to: (1) Prevent regurgitation of stomach contents (2) So that the weight measured just prior to anesthesia is more apt to represent a true value. b. Stage 3 surgical anesthesia plane characterized by: (1) Flaccid skeletal muscles (2) Disappearance of reflex responses (3) Shallow, regular respiration.
- Immediate hypersensitivity reaction of the lung was discovered in guinea pigs more than 100 years ago [6]. Preclinical pharmacological studies performed in guinea pigs have proven indispensable to the development of therapies for a wide range of respiratory diseases [7]. The relevance of these therapies to respiratory diseases was often first described in studies performed in guinea pigs.
